Publications

2007:

• Ohnmacht, C., Pullner, A., Van Rooijen, N., Voehringer, D., 2007. Analysis of eosinophil turnover in vivo reveals their active recruitment to and prolonged survival in the peritoneal cavity. J. Immunol.. vol. 179. pp. 4766-4774. (#409)



• Junt, T., Moseman, E.A., Iannacone, M., Massberg, S., Lang, P.A., Boes, M., Fink, K., Henrickson, S.E., Shayakhmetov, D.M., Van Rooijen, N., Mempel, T., Whelan, S.P., Von Adrian, U.H. , 2007. Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells. Nature. vol. 450. pp. 110-114. (#408)



• Borders, A.S., Hersh, M.A., Getchell, M.L., Van Rooijen, N., Cohen, D.A., Stromberg, A.J., Getchell, T.V. , 2007. Macrophage-mediated neuroprotection and neurogenesis in the olfactory epithelium. Physiol. Genomics. vol. 31. pp. 531-543. (#407)



• Price, J.D., Simpfendorfer, K.R., Mantena, R.R., Holden, J., Heath, W.R., Van Rooijen, N., Strugnell, R.A., Wijburg, O.L.C. , 2007. Gamma interferon-independent effects of interleukin-12 on immunity to Salmonella enterica serovar Typhimurium. Infect. Immun.. vol. 75. pp. 5753-5762. (#406)



• Kolaczkowska, E., Lelito, M., Kozakiewicz, E., Van Rooijen, N., Plytycz, B., Arnold, B. , 2007. Resident peritoneal leukocytes are important sources of MMP-9 during zymosan peritonitis: Superior contribution of macrophages over mast cells. Immunol. Lett.. vol. 113. pp. 99-106. (#405)



• Khandelwal, S., Van Rooijen, N., Saxena, R.K. , 2007. Reduced expression of CD47 during murine red blood cell (RBC) senescence and its role in RBC clearance from the circulation. Transfusion. vol. 47. pp. 1725-1732. (#404)



• Huang, Y., Cen, L-P., Choy, K.W., van Rooijen, N., Wang, N., Pang, C.P., Cui, Q. , 2007. JAK/STAT pathway mediates retinal ganglion cell survival after acute ocular hypertension but not under normal condition. Exp. Eye Res.. vol. 85. pp. 684-695. (#402)



• Huang, Y., Li, Z., Van Rooijen, N., Wang, N., Pang, C.P., Cui, Q. , 2007. Different responses of macrophages in retinal ganglion cell survival after acute ocular hypertension in rats with different autoimmune backgrounds. Exp. Eye Res.. vol. 85. pp. 659-666. (#401)



• Galea, I., Bernardes-Silva, M., Forse, P.A., Van Rooijen, N., Liblau, R.S., Perry, V.H. , 2007. An antigen-specific pathway for CD8 T cells across the blood-brain barrier. J. Exp. Med.. vol. 204. pp. 2023-2030. (#400)



• Dipasquale, D.M., Cheng, M., Billich, W., Huang, S.A., Van Rooijen, N., Hornberger, T., Koh, T.J. , 2007. Urokinase-type plasminogen activator and macrophages are required for skeletal muscle hypertrophy in mice. Am. J. Physiol. Cell Physiol. . vol. 293. pp. C1278-1285. (#399)



• Wang, H., Madariaga, M.L., Wang, S., Van Rooijen, N., Oldenborg, P-A., Yang, Y-G. , 2007. Lack of CD47 on non-hematopoietic cells induces split macrophage tolerance to CD47null cells. Proc. Natl. Acad. Sci. U S A. vol. 104. pp. 13744-13749. (#397)



• Gonzalez, N.C., Allen, J., Blanco, V.G., Schmidt, E.J., Van Rooijen, N., Wood, J.G. , 2007. Alveolar macrophages are necessary for the systemic inflammation of alveolar hypoxia. J. Appl. Physiol.. vol. 103. pp. 1386-1394. (#396)



• Kumar, K.A., Garcia, C.R.S., Chandran, V.R., Van Rooijen, N., Zhou, Y., Winzeler, E., Nussenzweig, V. , 2007. Exposure of Plasmodium sporozoites to the intracellular concentration of potassium enhances infectivity and reduces cell pasage activity. Molec. Biochem. Parasitol.. vol. 156. pp. 32-40. (#395)



• Fulci, G., Dmitrieva, N., Gianni, D., Fontana, E.J., Pan, X., Lu, Y., Kaufman, C,S., Kaur, B., Lawler, S.E., Lee, R.J., Marsh, C.B., Brat, D.J., Van Rooijen, N., Rachamimov, A.S., Hochberg, F.H., Weissleder, R., Martuza, R.L., Chiocca, E.A., 2007. Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses. Cancer Res.. vol. 67. pp. 9398-9406. (#394)



• Greten, F.R., Arkan, M.C., Bollrath, J., Hsu, L-C., Goode, J., Miething, C., Göktuna, S.I., Neuenhahn, M., Fierer, J., Paxian, S., Van Rooijen, N., Xu, Y., O’Cain, T., Jaffee, B.B., Busch, D.H., Duyster, J., Schmid, R.M., Eckmann, L., Karin, M. , 2007. NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta. Cell. vol. 130. pp. 918-931. (#393)



• Luo, J.M., Cen, L.P., Zhang, X-M., Chiang, S.W.Y., Huang, Y., Lin, D., Fan, Y.M., Van Rooijen, N., Lam, D.S.C., Pang, C.P., Cui, Q. , 2007. P13K/akt, JAK/STAT and MEK/ERK pathway inhibition protects retinal ganglion cells via different mechanisms after optic nerve injury. Eur. J. Neurosci.. vol. 26. pp. 828-842. (#392)



• Bauer, D., Wasmuth, S., Hermans, P., Hennig, M., Meller, K., Meller, D., Van Rooijen, N., Tseng, S.C.G., Steuhl, K-P., Heiligenhaus, A. , 2007. On the influence of neutrophils in corneas with necrotizing HSV-1 keratitis following amniotic membrane transplantation. Exp. Eye Res.. vol. 85. pp. 335-345. (#391)



• Rivera, C.A., Adegboyega, P., Van Rooijen, N., Tagalicud, A., Allman, M., Wallace, M., 2007. Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis. J. Hepatol.. vol. 47. pp. 571-579. (#390)



• Reese, T.A., Liang, H-E., Tager, A.M., Luster, A.D., Van Rooijen, N., Voehringer, D., Locksley, R.M. , 2007. Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature. vol. 447. pp. 92-96. (#389)



• Cen, L-P., Luo, J-M., Zhang, C-W., Fan, Y-M., Song, Y., So, K-F., Van Rooijen, N., Pang, C-P., Lam, D.S.C., Cui, Q. , 2007. Chemotactic effect of ciliary neurotrophic factor on macrophages in retinal ganglion cell survival and axonal regeneration. Invest. Ophthalmol. Vis. Res.. vol. 48. pp. 4257-4266. (#387)



• Arnold, L., Henry, A., Poron, F., Baba-Amer, Y., Van Rooijen, N., Plonquet, A., Gherardi, R.K., Chazaud, B. , 2007. Inflammatory monocytes recruited after sceletal muscle injury switch into anti-inflammatory macrophages to support myogenesis. J. Exp. Med.. vol. 204. pp. 1057-1069. (#386)



• Robinson-Smith, T.M., Isaacsohn, I., Mercer, C.A., Zhou, M., Van Rooijen, N., Husseinzadeh, N., McFarland-Mancini, M., Drew, A.F. , 2007. Macrophages mediate inflammation-enhanced metastasis of ovarian tumors in mice. Cancer Res.. vol. 67. pp. 5708-5716. (#385)



• Van Amerongen, M.J., Harmsen, M.C., Van Rooijen, N., Petersen, A.H., Van Luyn, M.J. , 2007. Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice. Am. J. Pathol.. vol. 170. pp. 818-829. (#384)



• Gazzaniga, S., Bravo, A., Guglielmotti, A., Van Rooijen, N., Maschi, F., Vecchi, A., Mantovani, A., Mordoh, J., Wainstok, R. , 2007. Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft. J. Invest. Dermatol.. vol. 127. pp. 2031-2041. (#383)



• Smith, P., Mangan, N.E., Walsh, C.M., Fallon, R.E., McKenzie, A.N.J., Van Rooijen, N., Fallon, P.G. , 2007. Infection with a Helminth parasite prevents experimental colitis via a macrophage-mediated mechanism. J. Immunol.. vol. 178. pp. 4557-4566. (#382)



• Voehringer, D., Van Rooijen, N., Locksley, R.M. , 2007. Eosinophils develop in distinct stages and are recruited to peripheral sites by alternatively activated macrophages. J. Leuk. Biol.. vol. 81. pp. 1434-1444. (#381)



• Carbonetti, N.H., Artamonova, G.V., Van Rooijen, N., Ayala, V.I. , 2007. Pertussis toxin targets airway macrophages to promote Bordetella pertussis infection of the respiratory tract. Infect. Immun.. vol. 75. pp. 1713-1720. (#380)



• Mocanu, J.D., Yip, K.W., Li, J-H., Lunt, S.J., Moriyama, E.H., Wilson, B.C., Lo, K.W., Van Rooijen, N., Milosevic, M., Bastianutto, C., Liu, F-F. , 2007. Imaging the modulation of adenoviral kinetics and biodistribution for cancer gene therapy. Mol. Ther.. vol. 15. pp. 921-929. (#379)



• Lundberg, P., Welander, P.V., Edwards, C.K. 3rd, van Rooijen, N., Cantin, E. , 2007. Tumor necrosis factor (TNF) protects resistant C57BL/6 mice against herpes simplex virus-induced encephalitis independently of signaling via TNF receptor 1 or 2. J. Virol.. vol. 81. pp. 1451-1460. (#378)



• Tacke, F., Llodra, J., Kaplan, T.J., Jakubzick, C., Liu, J., Van Rooijen, N., Randolph, G.J. , 2007. Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques. J. Clin. Invest. . vol. 117. pp. 185-194. (#377)



• Gray, M., Popovich, P.G., Van Rooijen, N., Gupta, R. , 2007. Macrophage depletion alters the blood nerve barrier without affecting Schwann cell function after neural injury. J. Neurosci. Res.. vol. 85. pp. 766-777. (#376)



• Borders, A.S., Getchell, M.L., Etscheidt, J.T., Van Rooijen, N., Cohen, D.A., Getchell, T.V. , 2007. Macrophage depletion in the murine olfactory epithelium leads to increased neuronal death and decreased neurogenesis. J. Compar. Neur.. vol. 501. pp. 206-218. (#375)



• Blom, A.B., Van Lent, P.L., Libregts, S., Holthuysen, A.E., Van der Kraan, P.M., Van Rooijen, N., Van den Berg, W.B. , 2007. Crucial role of macrophages in matrix metalloproteinase-mediated cartilage destruction during experimental osteoarthritis: Involvement of matrix metalloproteinase 3. Arthritis Rheum.. vol. 56. pp. 147-157. (#372)



• McEarchern, J.A., Oflazoglu, E., Francisco, L., McDonagh, C.F., Gordon, K.A., Stone, I., Klussman, K., Turcott, E., Van Rooijen, N., Carter, P., Grewal, I.S., Wahl, A.F., Leung Law, C. , 2007. Engineered anti-CD70 antibody with multiple effector functions exhibits in vitro and in vivo antitumor activities. Blood. vol. 109. pp. 1185-1192. (#371)



• Baer, K., Roosevelt, M., Clarkson Jr., A.B., Van Rooijen, N., Schnieder, T., Frevert, U. , 2007. Kupffer cells are obligatory for Plasmodium yoelii sporozoite infection of the liver. Cell. Microbiol. vol. 9. pp. 397-412. (#368)

2006:

• Furtado, G.C., Pina, B., Tacke, F., Gaupp, S., Van Rooijen, N., Moran, T.M., Randolph, G.J., Ransohoff, R.M., Chensue, S.W., Raine, C.S., Lira, S.A. , 2006. A novel model of demyelinating encephalomyelitis induced by monocytes and dendritic cells. J. Immunol.. vol. 177. pp. 6871-6879. (#374)



• Van Rooijen, N., Van Kesteren-Hendrikx, E. , 2006. The liposome mediated Macrophage Suicide Technique: A tool to study and manipulate macrophage activities.. In: “Liposome Technology” third edition, . vol. III, Gregory Gregoriadis ed. Informa Healthcare, USA.. pp. 303-316, (Chapter 16). (#373)



• Breitbach, K., Klocke, S., Tschernig, T., Van Rooijen, N., Baumann, U., Steinmetz, I. , 2006. Role of inducible nitric oxide synthase and NADPH oxidase in the early control of Burkholderia pseudomallei infection in mice. Infect. Immun.. vol. 74. pp. 6300-6309. (#370)



• Crettaz, J., Berraondo, P., Mauleon, I., Ochoa, L., Shankar, V., Barajas, M., Van Rooijen, N., Kochanek, S., Qian, C., Prieto, J., Hernandez-Alcoceba, R., Gonzales-Asequinolaza, G. , 2006. Intrahepatic injection of adenovirus reduces inflammation and increases gene transfer and therapeutic effect in mice. Hepatology. vol. 44. pp. 623-632. (#369)



• Anthony, R.M., Urban Jr, J.F., Alem, F., Hamed, H.A., Rozo, C.T., Boucher, J-L., Van Rooijen, N., Gause, W.C. , 2006. Memory TH2 cells induce alternatively activated macrophages to mediate protection against nematode parasites. Nature Medicine. vol. 12. pp. 955-960. (#367)



• Wang, H., Peters, T., Kess, D., Sindrilaru, A., Oreshkova, T., Van Rooijen, N., Stratis, A., Renkl, A.C., Sunderkötter, C., Wlaschek, M., Haase, I., Scharffetter-Kochanek, K. 2006. , 2006. Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation. J. Clin. Invest. . vol. 116. pp. 2105-2114. (#366)



• Stratis, A., Pasparakis, M., Rupec, R.A., Markur, D., Hartmann, K., Scharffetter-Kochanek, K., Peters, T., Van Rooijen, N., Krieg, T., Haase, I. , 2006. Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation. J. Clin. Invest. . vol. 116. pp. 2094-2104. (#365)



• Keijser, S., De Keizer, R.J.W., Prins, F.A., Tanke, H.J., Van Rooijen, N., Vrensen, G.F.J.M., Jager, M.J. , 2006. A new model for limbal transplantation using E-GFP for follow-up of transplant survival. Exp. Eye Res.. vol. 83. pp. 1188-1195. (#364)



• Louten, J., Van Rooijen, N., Biron, C.A. , 2006. Type 1 IFN deficiency in the absence of normal splenic architecture during lymphocytic choriomeningitis virus infection. J. Immunol.. vol. 177. pp. 3266-3272.. (#363)



• Synowitz, M., Glass, R., Faerber, K., Markovic, D., Kronenberg, G., Herrmann, K., Schnermann, J., Nolte, C., Van Rooijen, N., Kiwit, J., Kettenmann, H. , 2006. A1 adenosine receptors in microglia control glioblastoma - host interaction. Cancer Res.. vol. 66. pp. 8550-8557. (#362)



• Bakker, E.N.T.P., Pistea, A., Spaan, J.A.E., Rolf, T., De Vries, C.J., Van Rooijen, N., Candi, E., Van Bavel, E. , 2006. Arteries in mice defiecient for tissue-type transglutaminase: Possible compensation by macrophage-derived factor XIII. Circul. Res.. vol. 99. pp. 86-92. (#361)



• Qualls, J.E., Kaplan, A.M., Van Rooijen, N., Cohen, D.A. , 2006. Suppression of experimental colitis by intestinal mononuclear phagocytes. J. Leuk. Biol.. vol. 80. pp. 802-815. (#360)



• Kolaczkowska, E., Scislowska-Czarnecka, A., Chadzinska, M., Plytycz, B., Van Rooijen, N., Opdenakker, G., Arnold, B. , 2006. Enhanced early vascular permeability in gelatinase B (MMP-9)-deficient mice: putative contribution of COX-1-derived PGE2 of macrophage origin. J. Leuk. Biol.. vol. 80. pp. 125-132. (#359)



• Agrawal, S., Anderson, P., Durbeej, M., Van Rooijen, N., Ivars, F., Opdenakker, G., Sorokin, L.M., 2006. Selective dystroglycan cleavage by macrophage gelatinases is essential for leukocyte extravasation in experimental autoimmune encephalomyelitis. J. Exp. Med.. vol. 203. pp. 1007-1019. (#358)



• Gehring, S., Dickson, E.M., San Martin, M.E., Van Rooijen, N., Papa, E.F., Harty, M.W., Tracy Jr, T.F., Gregory, S.H. , 2006. Kupffer cells abrogate cholestatic liver injury in mice. Gastroenterology. vol. 130. pp. 810-822. (#357)



• Morosan, S., Hez-Deroubaix, S., Lunel, F., Renia, L., Giannini, C., Van Rooijen, N., Battaglia, S., Blanc, C., Eling, W., Sauerwein, R., Hannoun, L., Belghiti, J., Brechot, C., Kremsdorf, D., Druilhe, P. , 2006. Liver-stage development of Plasmodium falciparum in a humanized mouse model. J. Infect. Dis.. vol. 193. pp. 996-1004. (#356)



• Boonman, Z.F.H.M., Schurmans, L.R.H.M., Van Rooijen, N., Melief, C.J.M., Toes, R.E.M., Jager, M.J. , 2006. Macrophages are vital in spontaneous intraocular tumor eradication. Invest. Ophthalmol. Vis. Res.. vol. 47. pp. 2959-2965. (#355)



• Golay, J., Cittera, E., Di Gaetano, N., Manganini, M., Mosca, M., Nebuloni, M., Van Rooijen, N., Vago, L., Introna, M. , 2006. The role of complement in the therapeutic activity of rituximab in a murine B lymphoma model homing in lymph nodes. Haematologica. Haematologica. vol. 91. pp. 176-183. (#354)



• Jakubzick, C., Tacke, F., Llodra, J., Van Rooijen, N., Randolph, G.J. , 2006. Modulation of dendritic cell trafficking to and from the airways. J. Immunol.. vol. 176. pp. 3578-3584. (#352)



• Tacke, F., Ginhoux, F., Jakubzick, C., Van Rooijen, N., Merad, M., Randolph, G.J. , 2006. Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery. J. Exp. Med.. vol. 203. pp. 583-597. (#351)



• Le Borgne, M., Etchart, N., Goubier, A., Lira, S.A., Sirard, J.C., Van Rooijen, N., Caux, C., Ait-Yahia, S., Vicari, A., Kaiserlian, D., Dubois, B., 2006. Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo. Immunity. vol. 24. pp. 191-201. (#350)



• Summan, M., Warren, G.L., Mercer, R., Chapman, R., Hulderman, T., Van Rooijen, N., Simeonova, P.P., 2006. Macrophages and skeletal muscle regeneration: A clodronate-containing liposome depletion study. Am. J. Physiol.. vol. 290. pp. R1488-R1495. (#349)



• Stevenson, M., Boos, E., Herbert, C., Hale, A., Green, N., Lyons, M., Chandler, L., Ulbrich, K., Van Rooijen, N., Mautner, V., Fisher, K., Seymour, L. , 2006. Chick embryo lethal orphan virus can be polymer-coated and retargeted to infect mammalian cells. Gene Therapy. vol. 13. pp. 356-368. (#348)



• Mangan, N.E., Van Rooijen, N., McKenzie, A.N.J., Fallon, P.G., 2006. Helminth-modified pulmonary immune response protects mice from allergen-induced airway hyperresponsiveness. J. Immunol.. vol. 176. pp. 138-147. (#347)



• Moreno, A., Ferrer, E., Arahuetes, S., Eguiluz, C., Van Rooijen, N., Benito, A. , 2006. The course of infections and pathology in immunomodulated NOD/LtSz-SCID mice inoculated with Plasmodium falciparum laboratory lines and clinical isolates. Int. J. Parasitol.. vol. 36. pp. 361-369. (#345)



• Frid, M.G., Brunetti, J.A., Burke, D.L., Carpenter, T.C., Davie, N.J., Reeves, J.T., Roedersheimer, M.T., Van Rooijen, N., Stenmark, K.R. , 2006. Hypoxia-induced pulmonary vascular remodeling requires recruitment of circulating mesenchymal precursors of a monocyte/macrophage lineage. Am. J. Pathol.. vol. 168. pp. 659-669. (#344)



• Cote, C.K., Van Rooijen, N., Welkos, S.L., 2006. Roles of macrophages and neutrophils in the early host response to Bacillus anthracis spores in a mouse model of infection. Infect. Immun.. vol. 74. pp. 469-480. (#343)



• Evans, K.J., Hansen, D.S., Van Rooijen, N., Buckingham, L.A., Schofield, L., 2006. Severe malarial anemia of low parasite burden in rodent models results from accelerated clearance of uninfected erythrocytes. Blood. vol. 107. pp. 1192-1199. (#342)



• Haque, A., Easton, A., Smith, D., O’Garra, A., Van Rooijen, N., Lertmemongkolchai, G., Titball, R.W., Bancroft, G.J., 2006. Role of T cells in innate and adaptive immunity against murine Burkholderia pseudomallei infection. J. Infect. Dis. vol. 193. pp. 370-379. (#335)

2005:

• Keller, M., Gerbes, A.L., Kulhanek-Heinze, S., Gerwig, T., Grutzner, U., Van Rooijen, N., Vollmar, A.M., Kiemer, A.K. , 2005. Hepatocyte cytoskeleton during ischemia and reperfusion - influence of ANP-mediated p38 MAPK activation. World J. Gastroenterol.. vol. 11. pp. 7418-7429. (#353)



• Lawlor, K.E., Wong, P.K.K., Campbell, I.K., Van Rooijen, N., Wicks, I.P. , 2005. Acute CD4+ T lymphocyte-dependent interleukin-1-driven arthritis selectively requires interleukin-2 and interleukin-4, joint macrophages, granulocyte-macrophage colony-stimulating factor, interleukin-6, and leukemia inhibitory factor. Arthritis Rheum.. vol. 52. pp. 3749-3754. (#346)



• Tumpey, T.M., Garcia-Sastre, A., Taubenberger, J.K., Palese, P., Swayne, D.E., Pantin-Jackwood, M.J., Schultz-Cherry, S., Solorzano, A., Van Rooijen, N., Katz, J.M., Basler, C.F., 2005. Pathogenicity of Influenza Viruses with Genes from the 1918 Pandemic Virus: Functional Roles of Alveolar Macrophages and Neutrophils in Limiting Virus Replication and Mortality in Mice. J. Virol.. vol. 79. pp. 14933-14944. (#341)



• Holtje, M., Hoffmann, A., Hofmann, F., Mucke, C., Grosse, G., Van Rooijen, N., Kettenmann, H., Just, I., Ahnert-Hilger, G., 2005. Role of Rho GTPase in astrocyte morphology and migratory response during in vitro wound healing. J. Neurochem.. vol. 95. pp. 1237-1248. (#340)



• Ciavarra, R.P., Taylor, L., Greene, A.R., Yousefieh, N., Horeth, D., Van Rooijen, N., Steel, C., Gregory, B., Birkenbach, M., Sekellick, M. , 2005. Impact of macrophage and dendritic cell subset elimination on antiviral immunity, viral clearance and production of type 1 interferon. Virology. vol. 342. pp. 177-189. (#338)



• Markovic, D.S., Glass, R., Synowitz, M., Van Rooijen, N., Kettenmann, H., 2005. Microglia stimulate the invasiveness of glioma cells by increasing the activity of metalloprotease-2. J. Neuropathol. Exp. Neurol.. vol. 64. pp. 754-762. (#337)



• Maruyama, K., Li, M., Cursiefen, C., Jackson, D.G., Keino, H., Tomita, M., Van Rooijen, N., Takenaka, H., D’Amore, P.A., Stein-Streilein, J., Losordo, D.W., Streilein, J.W., 2005. Inflammation-induced lymphangiogenesis in the corona arises from CD11b-positive macrophages. J. Clin. Invest. . vol. 115. pp. 2363-2372. (#336)



• Ali, S., King, G.D., Curtin, J.F., Candolfi, M., Xiong, W., Liu, C., Puntel, M., Cheng, Q., Prieto, J., Ribas, A., Kupiec-Weglinski, J., Van Rooijen, N., Lassmann, H., Lowenstein, P.R., Castro, M.G. , 2005. Combined immunostimulation and conditional cytotoxic gene therapy provide long-term survival in a large glioma model. Cancer Res.. vol. 65. pp. 7194-7204. (#334)



• Oosterling, S.J., Van Der Bij, G.J., Meijer, G.A., Tuk, C. W., Van Garderen, E., Van Rooijen, N., Meijer, S., Van Der Sijp, J.R.M., Beelen, R.H.J., Van Egmond, M., 2005. Macrophages direct tumour histology and clinical outcome in a colon cancer model. J. Pathol.. vol. 207. pp. 147-155. (#333)



• Kresse, M., Latta, M., Kunstle, G., Riehle, H-M., Van Rooijen, N., Hentze, H., Tiegs, G., Biburger, M., Lucas, R., Wendel, A. , 2005. Kupffer cell expresses membrane-bound TNF and mediates Melphalan hepatoxicity via activation of both TNF receptors. J. Immunol.. vol. 175. pp. 4076-4083. (#332)



• Shao, X., Mednick, A., Alvarez, M., Van Rooijen, N., Casadevall, A., Goldman, D.L. , 2005. An innate immune system cell is a major determinant of species-related susceptibility differences to fungal pneumonia. J. Immunol.. vol. 175 . pp. 3244-3251. (#331)



• Newman, T.A., Galea, I., Van Rooijen, N., Perry, V.H. , 2005. Blood-derived dendritic cells in an acute brain injury. J. Neuroimmunol.. vol. 166. pp. 167-172. (#330)



• Fukushima, A., Ozaki, A., Ishida, W., Van Rooijen, N., Fukata, K., Ueno, H., 2005. Suppression of macrophage infiltration into the conjunctiva by clodronate liposomes in experimental immune-mediated blepharoconjunctivitis. Cell Biol. Int. . vol. 29. pp. 277-286. (#329)



• Nierkens, S., Bleumink, R., Bol, M., Hassing, I., Van Rooijen, N., Pieters, R. , 2005. The Reactive d-glucopyranose moiety of streptozotocin is responsible for activation of macrophages and subsequent stimulation of CD8(+) T cells. Chem. Res. Toxicol. . vol. 18. pp. 872-879. (#328)



• Ezendam, J., Kosterman, K., Spijkerboer, H., Bleumink, R., Hassing, I., Van Rooijen, N., Vos, J.G., Pieters, R., 2005. Macrophages are involved in hexachlorobenzene-induced adverse immune effects. Tox. Appl. Pharmacol. . vol. 209. pp. 19-27. (#327)



• Machemer, T., Engler, H., Tsai, V., Lee, S., Cannon-Carlson, S., Voloch, M., Schluep, T., Ravindran, S., Vellekamp, G., Brin, E., Cornell, D., Sutjipto, S., Fen Wen, S., Horn, M., Van Rooijen, N., Maneval, D., Hutchins, B., LaFace, D. , 2005. Characterization of hemodynamic events following intravascular infusion of recombinant adenovirus reveals possible solutions for mitigating cardiovascular responses. Mol. Ther.. vol. 12. pp. 254-263. (#326)



• Bustuoabad, O.D., Ruggiero, R.A., Di Gianni, P., Lombardi, M.G., Belli, C., Camerano, G.V., Dran, G., Schere-Levy, C., Costa, H., Isturiz, M.A., Narvaitz, M., Van Rooijen, N., Bustuoabad, V. de L., Meiss, R.P. , 2005. Tumor transition zone: a putative new morphological and functional hallmark of tumor aggressiveness. Oncol. Res.. vol. 15. pp. 169-182. (#325)



• Stamatovic, S.M., Shakui, P., Keep, R.F., Moore, B.B., Kunkel, S.L., Van Rooijen, N., Andjelkovic, A.V., 2005. Monocyte chemoattractant protein-1 regulation of blood-brain barrier permeability . J. Cereb. Blood Flow Metab. . vol. 25. pp. 593-606. (#324)



• Skokowa, J., Ali, S.R., Felda, O., Kumar, V., Konrad, S., Shushakova, N., Schmidt, R.E., Piekorz, R.P., Nurnberg, B., Spicher, K., Birnbaumer, L., Zwirner,, J., Claassens, J.W.C., Verbeek, J.S., van Rooijen, N., Kohl, J., Gessner, J.E. , 2005. Macrophages induce the inflammatory response in the pulmonary Arthus reaction through Galphai2 activation that controls C5aR and Fc receptor cooperation. J. Immunol.. vol. 174. pp. 3041 - 3050. (#323)



• Lou, D.Q., Lesbordes, J.C., Nicolas, G., Viatte. L., Bennoun, M., Van Rooijen, N., Kahn, A., Renia, L., Vaulont, S., 2005. Iron- and inflammation-induced hepcidin gene expression is not mediated by Kupffer cells in vivo. Hepatology. vol. 41. pp. 1056-1064. (#322)



• Schmieg, J., Yang, G., Franck,R.W., Van Rooijen, N., Tsuji, M., 2005. Glycolipid presentation to natural killer T cells differs in an organ-dependent fashion . Proc. Natl. Acad. Sci. U S A. vol. 102. pp. 1127-1132. (#320)



• Nemmar, A., Nemery, B., Hoet, P.H.M., Van Rooijen, N., Hoylaerts, M.F., 2005. Silica particles enhance peripheral thrombosis: key role of lung macrophage-neutrophil cross-talk . Am. J. Respir. Crit. Care Med. . vol. 171. pp. 872-879. (#319)



• Tribulatti, M.V., Mucci, J., Van Rooijen, N., Leguizamon, M.S., Campetella, O., 2005. The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas’ disease by reducing the platelet sialic acid contents. Infect. Immun.. vol. 73. pp. 201-207. (#318)



• Geier, A., Zollner, G., Dietrich, C.G., Wagner, M., Fickert, P., Denk, H., Van Rooijen, N., Matern, S., Gartung, C., Trauner, M., 2005. Cytokine-independent repression of rodent Ntcp in obstructive cholestasis. Hepatology. vol. 41. pp. 470-477. (#316)



• Leemans, J.C., Thepen, T., Weijer, S., Florquin, S., Van Rooijen, N., Van de Winkel, J.G., Van der Poll, T. , 2005. Macrophages play a dual role during pulmonary tuberculosis in mice. J. Infect. Dis. vol. 191. pp. 65-74. (#315)



• Nikolic, T., Geutskens, S.B., Van Rooijen, N., Drexhage, H.A., Leenen, P.J.M. , 2005. Dendritic cells and macrophages are essential for the retention of lymphocytes in (peri)-insulitis of the non-obese diabetic mouse: A phagocyte depletion study. Laboratory investigation. vol. 85. pp. 487-501. (#314)



• Sturm, E., Havinga, R., Baller, J.F.W., Wolters, H., Van Rooijen, N., Kamps, J.A.A.M., Verkade, H.J., Karpen, S.J., Kuipers, F. , 2005. Kupffer cell depletion with liposomal clodronate prevents suppression of Ntcp expression in endotoxin-treated rats. J. Hepatol.. vol. 42. pp. 102-109. (#313)



• Garzon, R.M., Berraondo, P., Crettaz, J., Ochoa, L., Vera, M., Lasarte, J.J., Vales, A., Van Rooijen, N., Ruiz, J., Prieto, J., Zulueta, J., Gonzalez-Aseguinolaza, G. , 2005. Induction of gp 120-specific protective immune responses by genetic vaccination with linear polyethylenimine-plasmid complex. Vaccine. vol. 23. pp. 1384-1392. (#312)



• Moreno,S.A., Moreno, M., Moreno,F.J., Eguiluz, C., Van Rooijen, N., Benito, A. , 2005. Experimental infection of immunomodulated NOD/LtSz-SCID mice as a new model for Plasmodium falciparum erythrocytic stages. Parasitol. Res.. vol. 95. pp. 97-105. (#311)



• Kotter, M.R., Zhao, C., Van Rooijen, N., Franklin, R.J.M., 2005. Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression. Neurobiol. Dis. . vol. 18. pp. 166-175. (#310)



• Galea, I., Newman, T., Palin, K., Van Rooijen, N., Perry, V.H., Boche, D., 2005. Mannose receptor expression specifically reveals perivascular macrophages in normal, injured and diseased mouse brain. Glia. vol. 49. pp. 375-384. (#301)

2004:

• Chadzinska, M., Kolaczkowska, E., Scislowska-Czarnecka, A., Van Rooijen, N., Plytycz, B. , 2004. Effects of macrophage depletion on peritoneal inflammation in swiss mice, edible frogs and goldfish. Folia Biologica (Krakow). vol. 52. pp. 225-231. (#321)



• Landoni, V.I., Vermeulen, M., Van Rooijen, N., Gomex, S., Palermo, M., Isturiz, M.A., Alves-Rosa, F., 2004. Macrophage derived signalling regulates negatively the megakaryocyte compartment. Cell Mol. Biol. . vol. 50. pp. OL667-OL675. (#317)



• Mangan, N.E., Fallon, R.E., Smith, P., Van Rooijen, N., McKenzie, A.N., Fallon, P.G. , 2004. Helminth infection protects mice from anaphylaxis via IL-10 producing B cells. J. Immunol.. vol. 173. pp. 6346-6356. (#309)



• Cote, C.K., Rea, K.M., Norris, S.L., Van Rooijen, N., Welkos, S.L. , 2004. The use of a model of in vivo macrophage depletion to study the role of macrophages during infection with Bacillus anthracis spores. Microb. Pathog. . vol. 37. pp. 169-175. (#308)



• Qu, C., Edwards, E.W., Tacke, F., Angeli, V., Llodra, J., Sanchez-Schmitz, G., Garin, A., Haque, N.S., Peters, W., Van Rooijen, N., Sanchez-Torres, C., Bromberg, J., Charo, I.F., Jung, S., Lira, S.A., Randolph, G.J. , 2004. Role of CCR8 and other chemokine pathways in the migration of monocyte-derived dendritic cells to lymph nodes. J. Exp. Med.. vol. 200. pp. 1231-1241. (#307)