Publications

1995:

• Huitinga,I., Ruuls,S.R., Jung,S., Van Rooijen,N., Hartung,H.-P. and Dijkstra,C.D., 1995. Macrophages in T cell line-mediated, demyelinating and chronic relapsing experimental autoimmu-ne encephalomyelitis in Lewis rats. Clin. Exp. Immunol.. vol. 100. pp. 344-351. (#103)



• Gaytan, F., Bellido, C., Morales, C., Van Rooijen, N. and Aguilar, E., 1995. Role of testicular macrophages in the response of Leydig cells to gonadotrophins in young hypophysectomized rats. J. Endocrinol.. vol. 147. pp. 463-471. (#102)



• Gaytan, F., Bellido, C., Morales, C., Reymundo, C., Aguilar, E. and Van Rooijen, N., 1995. Response to Leydig cell apoptosis in the absence of testicular macrophages. J. Reprod. Immunol.. vol. 29. pp. 81-94. (#101)



• Gaytan, F., Bellido, C., Aguilar, E. and Van Rooijen, N., 1995. Pituitary-testicular axis in rats lacking testicular macrophages. Eur. J. Endocrinol.. vol. 132. pp. 218-222. (#100)



• Buiting, A.M.J., De Rover, Z. And Van Rooijen, N., 1995. Brucella abortis causes an accellerated repopulation of the spleen and liver of mice by macrophages after their liposome-mediated depletion. J. Med. Microbiol.. vol. 42. pp. 133-140. (#99)



• Badell,E., Pasquetto,V.,Van Rooijen,N. and Druilhe,P., 1995. A mouse model for human malaria erythrocytic stages. Parasitology Today. vol. 11. pp. 235-237. (#98)



• Nair,S., Buiting, A.M.J., Van Rooijen,N., Huang,L. and Rouse,B.T., 1995. Role of macrophages and dendritic cells in primary cytotoxic T lymphocyte responses. Int.Immunol.. vol. 7. pp. 679-688. (#97)



• Bohm, W., Schirmbeck, R., Elbe, A., Melber, K., Diminsky, D., Kraal, G., Van Rooijen, N., Barenholz, Y. and Reimann, J., 1995. Exogenous hepatitis B surface antigen particles processed by dendritic cells or macrophages prime murine MHC class I-restricted cytotoxic T lymphocytes in vivo. J. Immunol.. vol. 155. pp. 3313-3321. (#96)



• Biewenga,J., Van der Ende,.B., Krist,L.F.G., Borst,A., Ghufron,M. and Van Rooijen,N., 1995. Macrophage depletion and repopulation in the rat after ip.administration of Cl2MBP- liposomes: Depletion kinetics and accelerated repopulation of peritoneal and omental macrophages by administration of Freund's adjuvant.. Cell Tissue Res.. vol. 280. pp. 189-196. (#95)



• Van Rooijen,N., 1995. Liposome mediated immunopotentiation and immunomodulation. In: "Vaccines: New Generation Immunological Adjuvants". NATO ASI Series A: G.Gregoriadis, B.McCormack & A.C.Allison Eds. Plenum Press, New York, USA.. vol. 282. pp. 15-24. (#94)



• Van Rooijen,N., 1995. Functional aspects of macrophages: Studies using the liposome mediated macrophage "suicide" approach. In "Liposomes: New systems and new trends in their applications". (F.Puisieux, P.Couvreur, J.Delattre and J.P.Devissaguet, eds.) Editions de Sante, Paris. pp. 711-734 (Chapter 25). (#93)



• Van Rooijen,N., Bakker,J., Sanders,A. and Mellink, J., 1995. Killing of Entamoeba invadens using liposome-encapsulated drugs. Parasitol. Res.. vol. 81. pp. 258-261. (#92)

1994:

• Van Velthuysen, M-L.F., Mayen, A., Van Rooijen, N., Fleuren,G.J., De Heer, E. And Bruyn, J.A., 1994. T-cells and macrophages in the pathogenesis of infection-related glomerulopathy. Infect. Immun.. vol. 62. pp. 3230-3235. (#91)



• Marquet,R.L., Bouwman,E., Bonthuis,F., Kouwenhoven,E., Van Rooijen,N., Scheringa,M. and IJzermans J.N.M., 1994. Local immunological factors determine the occurrence of primary nonfunction of islet xenografts. Transpl. Proc.. vol. 26. pp. 766-767. (#90)



• Marquet, R.L., Bonthuis, F., Van Ijken, M., Bouwman, E., Wolvekamp. M.C.J., Van Rooijen,N.,Scheringa,M. and IJzermans J.N.M., 1994. Primary nonfunction of islet xenografts: The role of macrophages. Transplant.Int. (Suppl.1). vol. 7. pp. 660-662. (#89)



• Marquette,C., Van Dam,A-M., Van Rooijen,N., Berkenbosch,F. and Haour,F., 1994. Peripheral macrophage depletion prevents downregulation of central interleukin-1 receptors in mice after endotoxin administration. Psychoneuroendocrinol.. vol. 19. pp. 189-196. (#88)



• Kurimoto,I., Van Rooijen,N., Dijkstra,C.D. and Streilein,J.W., 1994. Role of phagocytic macrophages in induction of contact hypersensitivity and tolerance by hapten applied to normal and ultraviolet B-irradiated skin. Immunology. vol. 82. pp. 281-287. (#87)



• Gaytan, F., Bellido, C., Aguilar, E. and Van Rooijen,N., 1994. Requirement for testicular macrophages in Leydig cell proliferation and differentiation during prepubertal development in rats. J. Reprod. Fertil.. vol. 102. pp. 393-399. (#86)



• Gaytan, F., Bellido, C., Morales, C., Reymundo, C., Aguilar, E. and Van Rooijen,N., 1994. Effects of macrophage depletion at different times after treatment with ethylene dimethane sulphonate (EDS) on the regeneration of Leydig cells in the adult rat. J. Androl.. vol. 15. pp. 558-564. (#85)



• Gaytan,F.,Bellido,C.,Morales,C.,Reymundo,C.,Aguilar,E. and Van Rooijen, N., 1994. Selective depletion of testicular macrophages and prevention of Leydig cell repopulation after treatment with ethylene dimethane sulfonate (EDS) in the rat. J. Reprod. Fertil.. vol. 101. pp. 175-182. (#84)



• Gonzalo, J.A., Baixeras, E., Gonzalez-Garcia, A., George-Chandy, A., Van Rooijen,N., Martinez, A.C. and Kroemer,G., 1994. Differential "in vivo" effects of a superantigen and an antibody targeted to the same T cell receptor. J. Immunol.. vol. 152. pp. 1597-1608. (#83)



• Qian, Q., Jutila, M.A., Van Rooijen, N. and Cutler, J.E., 1994. Elimination of mouse splenic macrophages correlates with increased susceptibility to experimental disseminated candidiasis. J. Immunol.. vol. 152. pp. 5000-5008. (#82)



• Berra,A., Rodriguez,A., Heiligenhaus,A., Pazos,B., Van Rooijen,N. and Foster,C.S., 1994. The role of macrophages in the pathogenesis of HSV-1 induced chorioretinitis in Balb/c mice. Invest.Ophthalmol.Vis. Sci. vol. 35. pp. 2990-2998. (#81)



• Van Der Veen,G.,Broersma,L.,Dijkstra,C.D.,Van Rooijen,N.,Van Rij,G.,Van Der Gaag,R., 1994. Prevention of corneal allograft rejection in rats treated with subconjunctival injections of liposomes containing dichloromethylene diphosphonate. Invest. Ophthalmol.. vol. 35. pp. 3505-3515. (#80)



• Litzinger,D.C.,Buiting,A.M.J.,Van Rooijen,N. and Huang,L., 1994. Effect of liposome size on the circulation time and intraorgan distribution of amphipathic polyethylene-glycol containing liposomes. Bioch. Bioph. Acta. vol. 1190. pp. 99-107. (#79)



• Wijffels, J.F.A.M., De Rover, Z., Beelen, R.H.J., Kraal, G. and Van Rooijen, N., 1994. Macrophage subpopulations in the spleen renewed by local proliferation. Immunobiology. vol. 191. pp. 52-64. (#78)



• Van Lent,P.L.E.M., Holthuyzen,A.E.M.,Van Den Bersselaar,L.A.M.,Van Rooijen,N., Van De Putte,L.B.A. and Van Den Berg, W.B., 1994. Phagocytic synovial lining cells in propagation and exacerbation of smouldering synovitis. Agents and Actions. vol. 41. pp. C206-C208. (#77)



• Van Lent,P.L.E.M., Van Den Bersselaar,L.A.M.,Holthuyzen,A.E.M.,Van Rooijen,N., Van De Putte,L.B.A. and Van Den Berg, W.B., 1994. Phagocytic synovial lining cells in experimentally induced chronic arthritis: Downregulation of synovitis by Cl2MDP-liposomes. Rheumatol. Int.. vol. 13. pp. 221-228. (#76)



• De Rijk,R.H.,Van Kampen,M.,Van Rooijen,N. and Berkenbosch,F., 1994. Hypothermia to bacterial endotoxin in rats at sub-thermoneutral ambient temperatures involves reduced thermogenesis and macrophage-dependent mechanisms and is mediated by prostaglandins. Am. J. Physiol.. vol. 266. pp. R1-R8. (#75)



• Buiting, A.M.J. and Van Rooijen, N., 1994. Liposome mediated depletion of macrophages: An approach for fundamental studies. J. Drug Targeting. vol. 2. pp. 357-362. (#74)



• Van Rooijen,N., 1994. Liposome mediated modulation of macrophage functions. In "In Vivo Immunology: Regulatory Processes During Lymphopoiesis and Immunopoiesis". (Heinen,E. Ed.), Plenum Publish. Corp., New York. pp. 69-74. (#73)



• Van Rooijen, N., 1994. Liposomes in host defense mechanism: A key role for macrophages. J. Liposome Research. vol. 4. pp. 193-201. (#72)



• Van Rooijen,N. and Sanders,A., 1994. Liposome mediated depletion of macrophages: Mechanism of action, preparation of liposomes and applications. J. Immunol. Meth.. vol. 174. pp. 83-93. (#71)

1993:

• Van Rooijen N. , 1993. The multiple accessory cell concept. Its relevance to the development of adjuvants and vaccines.. In: “New generation vaccines: Its relevance to the development of adjuvants and vaccines” (Gregoriadis G. Ed.), Plenum Press. NY, USA.. pp. 11-22. (#925)



• Van Rooijen, N. , 1993. The role of the FDC-retained immune complex network and its dynamics in the actvity of germinal centers. Res. Immunol.. vol. 144. pp. 545-552. (#924)



• Buiting, A.M.J., De Rover, Z., Claassen, E., Van Rooijen, N. , 1993. In vivo distribution of particulate antigens and liposomes in murine spleen. A possible role in the humoral immune response. Immunobiology. vol. 188. pp. 13-22. (#748)



• Dulak, J., Bauer, J., Dopp, E.A., Van Rooijen, N. , 1993. Immune complex trapping cells in the spleen of oriental firebellied toad “Bombina orientalis”. Cell Tissue Res.. vol. 271. pp. 155-158. (#747)



• Van den Dobbelsteen,G.P.J.M.,Brunekreef,K.,Kroes,H.,Van Rooijen,N. and Van Rees,E.P., 1993. Enhanced triggering of mucosal immune responses by reducing splenic phagocytic functions. Eur. J. Immunol.. vol. 23. pp. 1488-1493. (#70)



• Nieuwenhuijzen, G.A.P., Haskel, Y., Lu, Q., Berg, R.D., Van Rooijen, N.,Goris,R.J.A. and Deitch,E.A., 1993. Macrophage elimination increases bacterial translocation and gut-origin septicemia but attenuates symtoms and mortality rate in a model of systemic inflammation. Annals Surg.. vol. 218. pp. 791-799. (#69)



• De Rijk,R.H., Strijbos,P.J.L.M.,Van Rooijen,N.,Rothwell,N.J.and Berkenbosch,F., 1993. Fever and thermogenesis in response to bacterial endotoxin (LPS) involves macrophage-dependent mechanisms in the rat. Am. J. Physiol.. vol. 265. pp. R1179-R1183. (#68)



• Curfs,J.H.A.J., Hermsen,C.C., Meuwissen,J.H.E.Th., Van Rooijen,N. and Eling W.M.C., 1993. Tumor necrosis factor-a and monocytes in Plasmodium Berghei-induced cerebral malaria. Parasitology. vol. 107. pp. 125-134. (#67)



• Van Lent, P.L.E.M.,Van De Hoek,A.,Van Den Bersselaar,L.,Van Rooijen,N. and Van Den Berg, W.B., 1993. Role of phagocytic synovial lining cells in experimental arthritis. Agents and Actions. vol. 38. pp. C92-C94. (#66)



• Van Lent,P.L.E.M., Van De Hoek,A., Van Den Bersselaar,L., Spanjaards, M.F.R.,Van Rooijen,N., Dijkstra,C.D., Van De Putte, L.B.A. and Van Den Berg, W.B., 1993. In vivo role of phagocytic synovial lining cells in onset of experimental arthritis. Am. J. Pathol.. vol. 143. pp. 1226-1237. (#65)



• Van Lent, P.L.E.M., Van Den Bersselaar, L., Van Den Hoek, A.E.M., Van De Ende, M., Dijkstra,C.D., Van Rooijen,N., Van De Putte, L.B.A. and Van Den Berg, W.B., 1993. Reversible depletion of synovial lining cells after intraarticular treatment with liposome encapsulated dichloromethylene diphosphonate. Rheumat.Intern.. vol. 13. pp. 21-30. (#64)



• Vreden,S.G.S., Sauerwein,R.W., Verhave,J.P., Van Rooijen,N., Meuwissen, J.H.E.T. and Van Den Broek,M.F., 1993. Kupffer cell elimination enhances the development of liver Schizonts of Plasmodium Berghei in rats. Infect. Immunity. vol. 61. pp. 1936-1939. (#63)



• Han,Y.,Van Rooijen,N. and Cutler,J.E., 1993. Binding of Candida albicans yeast cells to mouse popliteal lymph node tissue is mediated by macrophages. Infect. Immunity. vol. 61. pp. 3244-3249. (#62)



• Huppes,W.,Paulonis,J.,Dijk,H., Van Rooijen,N. and Van Bekkum,D.W., 1993. The role of natural antibodies and ABO(H) blood groups in transplanta- tion of human lymphoid cells into mice. Eur. J. Immunol.. vol. 23. pp. 26-32. (#61)



• Heuff,G.,Boutkan,H.,Beelen,R.H.J.,Van Rooijen,N.,Meyer,S. and Dijkstra, C.D., 1993. Kinetics and functional role of Kupffer cells in controlling hepatic metastasis. In "Cells of the hepatic sinusoid"(Knook D.L. and Wisse,E. eds.). vol. 4. pp. 500-503. (#60)



• Heuff,G., Oldenburg,H.S.A., Boutkan,H., Visser,J.J., Beelen,R.H.J., Van Rooijen,N., Dijkstra,C.D. and Meyer,S., 1993. Enhanced tumour growth in the rat liver after selective elimination of Kupffer cells. Cancer Immunol. Immunother. . vol. 37. pp. 125-130. (#59)



• Coremans,I.E.M., Bogers,W.M.J.M.,Stad,R.K., Van der Voort,E.A.M.,Prins, F.A.,Van Rooijen,N.,Breedveld,F.C. and Daha,M.R., 1993. Role of liver endothelial and Kupffer cells in clearance of human C1q in rats. Eur. J. Immunol.. vol. 23. pp. 1942-1947. (#58)



• Bogers, W.M.J.M., Van Rooijen, N., Janssen, D.J.,Van Es, L.A. and Daha, M.R., 1993. Complement enhances the elimination of soluble aggregates of IgG by rat liver endothelial cells in vivo. Eur. J. Immunol.. vol. 23. pp. 433-438. (#57)



• Bette,M.,Schafer,M.K.H.,Van Rooijen,N.,Weihe,E. and Fleischer,B., 1993. Distribution and kinetics of superantigen-induced cytokine gene expression in mouse spleen. J. Exp. Med.. vol. 178. pp. 1531-1540. (#56)



• Berkenbosch,F.,Van Rooijen,N. and Tilders,F.J.H., 1993. Determining role and sources of endogenous interleukin-1 in pituitary-adrenal activation in response to stressful and inflammatory stimuli. In: "Methods in Neurosciences": Neurobiology of cytokines, Part A (De Souza,E.B. Ed.). vol. 16. pp. 211-231. (#55)



• Bergh, A., Damber, J-E, and Van Rooijen, N., 1993. The HCG-induced inflammation-like response is enhanced in macrophage-depleted testes. J. Endocrinol.. vol. 136. pp. 415-420. (#54)



• Bergh, A., Damber, J-E, and Van Rooijen, N., 1993. Liposome-mediated macrophage depletion: An experimental approach to study the role of testicular macrophages. J. Endocrinol.. vol. 136. pp. 407-413. (#53)



• Van Rooijen, N., 1993. Immunoadjuvant activities of liposomes: Two different macrophage mediated mechanisms. Vaccine. vol. 11. pp. 1170. (#52)



• Van Rooijen, N., 1993. Extracellular and intracellular action of clodronate in osteolytic bone diseases: A hypothesis. Calcified Tiss. Internat.. vol. 52. pp. 407-410. (#51)

1992:

• Van Rooijen, N. , 1992. Follicular Dendritic Cell (FDC)-B cell interaction in virus disease: Common localization but different cell damage caused by antibody immobilized virus? . Arch. Virol.. vol. 122. pp. 215-218. (#753)



• Van Rooijen, N. , 1992. Lipopolysaccharide, Lipid A or monophosphoryl-lipid A for eliciting antibodies against surface antigens on liposomes or irradiated tumour cells. 44th Forum in Immunology. Res. Immunol.. vol. 143. pp. 578-579. (#752)



• Van Rooijen, N., Ter Hart, H., Kraal, G., Kors, N., Claassen, E. , 1992. Monoclonal antibody targeting of enzymes: A comparative study using the mouse spleen as a model system. J. Immunol. Meth.. vol. 151. pp. 149-155. (#751)



• Laman, J.D., Van Eertwegh, A.J.M., Claassen, E., van Rooijen, N. , 1992. Cell-cell interactions: “In situ” studies of splenic humoral immune responses. In: Immune system accessory cells. Eds. L. Fornusek and V. Vetvicka. CRC Press, U.S.A. . vol. Chapter 10. pp. 201-231. (#750)



• Laman, J.D., Van Eertwegh, A.J.M., Claassen, E., van Rooijen, N. , 1992. Production of a monomeric antigen-enzyme conjugate to study requirements for follicular immune complex trapping. Histochemistry. vol. 97. pp. 189-194. (#749)



• Buiting, A.M.J., Van Rooijen,N. and Claassen,E., 1992. Liposomes as antigen carriers and adjuvants "in vivo" In: 44th Forum in Immunology . Res. Immunol.. vol. 143. pp. 541-548. (#50)



• Huitinga,I.,Damoiseaux,J.G.M.C.,Van Rooijen.N., Dopp,E.A. and Dijkstra, C.D., 1992. Liposome mediated affection of monocytes. Immunobiology. vol. 185. pp. 11-19. (#49)



• Van Lent, P.L.E.M., Van den Hoek,A., Van den Bersselaar, Dijkstra,C.D., Van Rooijen,N. and Van den Berg W.B., 1992. Role of synovial macrophages in experimental arthritis. In: 41st Forum in Immunology . Res. Immunol.. vol. 143. pp. 229-234. (#48)



• De Rijk, R.H., Van Rooijen,N. and Berkenbosch,F., 1992. The role of macrophages in the hypothalamic-pituitary-adrenal activation in response to endotoxin (LPS)In: 41st Forum in Immunology . Res. Immunol.. vol. 143. pp. 224-229. (#47)



• Van Rooijen, N. and Poppema, A., 1992. Efficacy of various water soluble chelator molecules in the liposome mediated macrophage "suicide" technique. J. Pharmacol. Meth.. vol. 28. pp. 217-221. (#46)



• Van Rooijen, N., 1992. Liposomes. In: Encyclopedia of Immunology. Eds. I.M. Roitt and P.J. Delves. W.B. Saunders Company. pp. 986-988. (#45)



• Van Rooijen, N., 1992. Liposome-mediated elimination of macrophages In 41st Forum in Immunology: Liposomes as an "in vivo" tool to study and manipulate macrophage function.. Res. Immunol.. vol. 143. pp. 215-219. (#44)



• Van Rooijen, N., 1992. Liposomes as an "in vivo" tool to study and manipulate macrophage function: Introduction 41st Forum in Immunology.. Res. Immunol.. vol. 143. pp. 177-178. (#43)



• Van Rooijen, N., 1992. Macrophages as accessory cells in the "in vivo" humoral immune response: From processing of particulate antigens to regulation by suppression. Semin. Immunol.. vol. 4 . pp. 237-245. (#42)

1991:

• Delemarre,,F.G.A., Kors,N. and Van Rooijen, N. , 1991. Development of antibody forming cells in follicles of lymph nodes of mice after continuous antigenic stimulation. Immunobiology. vol. 184. pp. 75-82. (#762)



• Wijffels, J.F.A.M., De Rover, Z., Van Rooijen, N., Kraal, G.,and Beelen, R.H.J. , 1991. Chronic inflammation induces the expression of dendritic cell markers, not related to functional antigen presentation on peritoneal exudate macrophages. Immunobiology. vol. 184. pp. 83-92. (#761)



• Wijffels, J.F.A.M., De Rover, Z., Van Rooijen, N., Kraal, G.,and Beelen, R.H.J. , 1991. Exudate macrophages can express dendritic cell markers in vitro. . In Lymphatic tissues and in vivo immune responses.(Imhof et al. eds.) Marcel Dekker, Inc. New York. vol. chapter142. pp. 827-831. (#760)



• Wijffels, J.F.A.M., De Rover, Z., Van Rooijen, N., Kraal, G.,and Beelen, R.H.J. , 1991. Clonal expansion of bone marrow-derived macrophage cell lines, which can be repopulated in vivo. In Lymphatic tissues and in vivo immune responses(Imhof et al. eds.) Marcel Dekker, Inc. New York. vol. chapter 140. pp. 815-819. (#759)



• Van Den Dobbelsteen, G.P.J.M., Van Rooijen, N., Sminia,,T.,,and Van Rees, E .P. , 1991. The immune response in the rat to streptococcus pneumoniae. J. Immunol. Meth.. vol. 145. pp. 93-103. (#758)



• Soesatyo M., Biewenga,J..,Van Rooijen, N. and Sminia, T. , 1991. The immune response of the rat to intestinally administered thymus dependent and thymus independent antigens: Role of Peyers patches in the regulation of specific antibody production. In Lymphatic tissues and in vivo immune responses (Imhof et al. eds.) Marcel Dekker, Inc. New York. vol. chapter 140. pp. 493-496. (#757)



• Van Rooijen, N. , 1991. Dual pathway for differentiation of memory B cells to antibody forming cells in the spleen. In Lymphatic tissues and in vivo immune responses".(Imhof et al. eds. (Marcel Dekker,,Inc New York . vol. chapter 69. pp. 413-416. (#756)



• Van Rooijen, N. , 1991. The humoral immune response in the spleen. Res. Immunol.. vol. 142. pp. 328-330. (#755)



• Van Rooijen, N. , 1991. The role of antigens, antibodies and immune complexes in the functional activity of germinal centers. . Res. Immunol.. vol. 142. pp. 272-275. (#754)



• Soesatyo,M., Biewenga,J., Van Rooijen,N., Kors,N., and Sminia,T., 1991. The "in situ" immune response of the rat after intraperitoneal depletion of macrophages by liposome-encapsulated dichloromethylene diphosphonate. Res. Immunol.. vol. 142. pp. 533-540. (#41)



• Monkkonen,J., Van Rooijen,N. and Ylitalo,P., 1991. Effects of clodronate and pamidronate on splenic and hepatic phagocytic cells of mice. Pharmacol. Toxicol.. vol. 68. pp. 284-286. (#40)



• Pinto,A.J., Stewart,D., Van Rooijen,N. and Morahan,P.S., 1991. Selective depletion of liver and splenic macrophages using liposomes encapsulating the drug dichloromethylene diphosphonate: Effects on antimicrobial resistance. J. Leuk. Biol.. vol. 49. pp. 579-586. (#39)



• Delemarre,F.G.A., Kors,N., and Van Rooijen,N., 1991. The role of the spleen and of lymph node macrophages in the immune response to particulate antigens. In " Lymphatic tissues and in vivo immune responses".(Imhof et al.eds.) Marcel Dekker,Inc. New York. pp. 843-847 (chapter 145). (#38)



• Delemarre,F.G.A., Kors,N. and Van Rooijen,N., 1991. Elimination of spleen and of lymph node macrophages and its difference in the effect on the immune response to particulate antigens. Immunobiology. vol. 182. pp. 70-78. (#37)



• De Rijk, R., Van Rooijen,N., Tilders, F., Besedovsky, H., Del Rey, A., and Berkenbosch, F., 1991. Selective depletion of macrophages prevents increased plasma interleukin-1 concentrations and pituitary-adrenal activation in response to endotoxin administration in rats. Endocrinology. vol. 129. pp. 330-338. (#36)



• Bogers, W.M.J.M., Stad,R.K., Janssen,D.J., Van Rooijen,N.,Van Es, L.A., Daha,M.R., 1991. Kupffer cell depletion "in vivo" results in preferential elimination of IgG aggregates and immune complexes via specific Fc receptors on rat liver endothelial cells. Clin. Exp. Immunol.. vol. 86. pp. 328-333. (#35)



• Bogers, W.M.J.M., Stad, R.K., Janssen, D.J., Prins, F.A., Van Rooijen, N., Van Es, L.A., and Daha, M.R., 1991. Kupffer cell depletion in vivo results in clearance of large sized IgA aggregates in rats by liver endothelial cells. Clin. Exp. Immunol.. vol. 85. pp. 128-136. (#34)



• Van Rooijen, N., 1991. High and low cytosolic Ca2+ induced macrophage death ?. Cell Calcium. vol. 12. pp. 381-384. (#33)

1990:

• Laman, J.D., Gerritse, K., Fasbender, M., Boersma, W.J.A., Van Rooijen, N., and Claassen, E. , 1990. Double immunocytochemical staining for the in vivo detection of epitope specificity and isotype of antibody forming cells against synthetic peptides homologous to human immunodefieciency viris-1. J. Histochem. Cytochem.. vol. 38. pp. 457-462. (#763)



• Van Rooijen, N., 1990. Direct intrafollicular differentiation of memory B-cells to plasma cells. Immunol. Today. vol. 11. pp. 154-157. (#743)



• Claassen, I., Van Rooijen, N., and Claassen, E., 1990. A new method for removal of mononuclear phagocytes from heterogenous cell populations 'in vitro', using the liposome-mediated macrophage 'suicide' technique. J. Immunol. Meth.. vol. 134. pp. 153-161. (#32)



• Huitinga, I., Van Rooijen, N., De Groot, C.J.A., Uitdehaag, B.M.J., and Dijkstra, C.D., 1990. Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages. J. Exp. Med.. vol. 172. pp. 1025-1033. (#31)



• Huitinga, I., Van Rooijen, N., De Groot, C.J.A., Uitdehaag, B.M.J., and Dijkstra, C.D., 1990. Elimination of macrophages infiltrating into the Central Nervous System suppresses experimental allergic encephalomyelitis in Lewis rats. Ann. N.Y. Acad. Sci.. vol. 594. pp. 458-460. (#30)



• Delemarre, F.G.A., Kors, N., Van Rooijen, N., 1990. The 'in situ' immune response in popliteal lymph nodes of mice after macrophage depletion. Differential effects of macrophages on thymus-dependent and thymus- independent immune responses.. Immunobiology. vol. 180. pp. 395-404. (#29)



• Delemarre, F.G.A., Kors, N., Kraal, G., Van Rooijen, N., 1990. Repopulation of macrophages in popliteal lymph nodes of mice after liposome mediated depletion. J. Leuk. Biol.. vol. 47. pp. 251-257. (#28)



• Laman, J.D., Kors, N., Van Rooijen, N., and Claassen, E., 1990. Mechanisms of follicular trapping: Localisation of immune complexes and cell remnants after elimination and repopulation of different spleen cell populations. Immunology. vol. 71. pp. 57-62. (#27)



• Van Rooijen, N., Kors, N., Van den Ende, M., Dijkstra, C.D., 1990. Depletion and repopulation of macrophages in spleen and liver of rat after intravenous treatment with liposome encapsulated dichloromethylene diphosphonate. Cell Tissue Res.. vol. 260. pp. 215-222. (#26)



• Van Rooijen, N., 1990. Antigen processing and presentation in vivo: The microenvironment as a crucial factor. Immunol. Today. vol. 11. pp. 436-439. (#25)



• Van Rooijen, N., 1990. Liposomes as carrier and immunoadjuvant of vaccine antigens. In: Bacterial vaccines. Ed. A. Mizrahi. Alan R. Liss, N.Y. USA. Adv. Biotechnol. Processes. vol. 13. pp. 255-279. (#24)